Search results for "Error threshold"

showing 3 items of 3 documents

Viral replication modes in single-peak fitness landscapes: A dynamical systems analysis

2017

Positive-sense, single-stranded RNA viruses are important pathogens infecting almost all types of organisms. Experimental evidence from distributions of mutations and from viral RNA amplification suggest that these pathogens may follow different RNA replication modes, ranging from the stamping machine replication (SMR) to the geometric replication (GR) mode. Although previous theoretical work has focused on the evolutionary dynamics of RNA viruses amplifying their genomes with different strategies, little is known in terms of the bifurcations and transitions involving the so-called error threshold (mutation-induced dominance of mutants) and lethal mutagenesis (extinction of all sequences du…

0301 basic medicineStatistics and ProbabilityRNA virusesMutation rateDynamical systems theoryFitness landscapeMutantBiologyVirus ReplicationGenomeModels BiologicalGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesBifurcations0302 clinical medicineMutation RateSingle-peak fitness landscapeError thresholdDynamical systemsReplication modesDifferentiable dynamical systemsEvolutionary dynamics51 - MatemàtiquesGenetics51General Immunology and MicrobiologyModels GeneticApplied MathematicsRNA:Matemàtiques i estadística [Àrees temàtiques de la UPC]General MedicineMutation AccumulationSistemes dinàmics diferenciables030104 developmental biologyViral replicationMutagenesisModeling and SimulationMatemàtiquesGeneral Agricultural and Biological Sciences030217 neurology & neurosurgery
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2005

In this report we re-examine some recent experiments with digital organisms to test some predictions of quasispecies theory. These experiments revealed that under high mutation rates populations of less fit organisms previously adapted to such high mutation rates were able to outcompete organisms with higher average fitness but adapted to low mutation rates. We have verified that these results do hold in the original conditions and, by extending the set of initial parameters, we have also detected that the critical mutation rate was independent of population size, a result that we have found to be dependent on a different, contingent factor, the initial fitness vector. Furthermore, in all b…

GeneticsMutation rateEvolutionary biologyPopulation sizeError thresholdGenetic variationMutation (genetic algorithm)Quasispecies theoryViral quasispeciesBiological evolutionBiologyEcology Evolution Behavior and SystematicsBMC Evolutionary Biology
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Enabling XCSF to cope with dynamic environments via an adaptive error threshold

2020

The learning classifier system XCSF is a variant of XCS employed for function approximation. Although XCSF is a promising candidate for deployment in autonomous systems, its parameter dependability imposes a significant hurdle, as a-priori parameter optimization is not feasible for complex and changing environmental conditions. One of the most important parameters is the error threshold, which can be interpreted as a target bound on the approximation error and has to be set according to the approximated function. To enable XCSF to reliably approximate functions that change during runtime, we propose the use of an error threshold, which is adapted at run-time based on the currently achieved …

Learning classifier systemComputer scienceError thresholdComputer Science::Neural and Evolutionary Computation0102 computer and information sciences02 engineering and technologyFunction (mathematics)01 natural sciencesSet (abstract data type)Function approximation010201 computation theory & mathematicsApproximation error0202 electrical engineering electronic engineering information engineering020201 artificial intelligence & image processingAlgorithmProceedings of the 2020 Genetic and Evolutionary Computation Conference Companion
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